Study of capillary transit time distribution in coherent hemodynamics spectrosco

A recently proposed analytical hemodynamic model1 [S. Fantini, NeuroImage 85, 202–221 (2014)] is able to predict the changes of oxy, deoxy, and total hemoglobin concentrations (model outputs) given arbitrary changes in blood flow, blood volume, and rate of oxygen consumption (model inputs). One assumption of this model is that the capillary compartment is characterized by a single blood transit time. In this work, we have extended the original model by considering a distribution of capillary tra