A miniaturized system for measurement of the refractive index of sub microliter

This study introduced the research and development of a portable and miniaturized system for the measurement of the refractive index of sub-microliter liquid based on a microfluidic chip. A technical method of double-beam interference, was proposed for use in the measurement. Based on this, by using a laser diode as a light source, changes in the refractive index were calculated by utilizing a complementary metal–oxide–semiconductor to detect the movement of interference fringes of the liquid. F